Nonverbal patients with Angelman syndrome do not necessarily differentiate between known names — their own or those of others…
Articles by José Lopes, PhD
Ovid Therapeutics is planning to start a pivotal Phase 3 trial of OV101 (gaboxadol), its investigational oral therapy, in…
Treatment candidate OV101 showed a favorable safety profile and was well-tolerated in adults and adolescents with Angelman syndrome…
A mutation in the UBE3A gene, whose loss causes Angelman syndrome, activates a molecular pathway that is critical to…
A specific type of magnetic resonance imaging (MRI) can be used to detect oxidative stress in mouse models of Angelman…
Patients with Angelman syndrome (AS) often have gastrointestinal (GI) issues such as constipation, reflux and abnormal food-related behaviors, according to…
Sleep problems in children with Angelman syndrome (AS), particularly abnormal nighttime duration and night-walking, start in early infancy, a new…
In a mouse model of Angelman syndrome (AS), pain sensitivity increased due to genetic alterations in the central nervous system,…
Sleep disturbances and epilepsy, which affect about 80 percent of pediatric Angelman syndrome patients, improve over the years, new Italian…
Sleep problems of children with Angelman syndrome (AS) take a toll on parents as well, according to a study that takes…