Posts by: Catarina Silva, MSc

Catarina Silva, MSc

With over three years of experience in the medical communications business, Catarina holds a BSc. in Biomedical Sciences and a MSc. in Neurosciences. Apart from writing, she has been involved in patient-oriented translational and clinical research.

May 20, 2019May 20, 2019

#AANAM – OV101 Improves Motor Function, Sleep, Behavior, Phase 2 Trial Shows

News

Ovid Therapeutics’ experimental therapy OV101 has been shown to improve sleep, motor function, communication skills, and reduce challenging behavior and anxiety in patients with Angelman syndrome in a Phase ... Read more

February 16, 2018February 16, 2018

Specific Eye Problems Should Hint at Possibility of Angelman’s, Case Report Suggests

News

Specific eye conditions may be a clue to diagnosing Angelman syndrome in patients who also have abnormalities consistent with other diseases, a case report suggests. The report, “A Case ... Read more

February 1, 2018

Angelman Syndrome Seizure Susceptibility Probed in UBE3A Mice

News

For the first time, researchers have characterized the nerve cell size and electrical activity in a key auditory area of the brain using a UBE3A gene mouse model. The findings may ... Read more

January 10, 2018

Nerve Fibers’ Thickness Linked to the Biology of Angelman Syndrome

News

Scientists have shown that thinner-than-normal nerve cell projections (axons) are involved in Angelman syndrome (AS) disease mechanism. The study, “Decreased Axon Caliber Underlies Loss of Fiber Tract Integrity, Disproportional ... Read more

November 14, 2017November 14, 2017

Statin Seen to Ease Seizures, Lessen Neuron Excitability in Angelman Mouse Model

News

A statin used to lower blood cholesterol levels, lovastatin, was seen to ease seizures and the excitatory neurotransmission that accompanies them in a mouse model of Angelman syndrome (AS)-associated epilepsy, ... Read more

October 19, 2017

Eye-Tracking Techniques Useful in Quantifying Social Impairment, Study Says

News

Angelman syndrome (AS) patients have a lower preference for social stimuli than typically developing individuals, a new study shows. Also, AS patients do not show increased pupil dilation in response ... Read more

October 18, 2017

UBE3A Loss Leads to Alterations in Genes Involved in Brain Development, Study Says

News

Decreasing UBE3A levels has a profound effect on the expression of multiple other genes, mostly due to chemical modifications in the DNA, a new study found. The research shows that ... Read more