The Angelman Syndrome Foundation has awarded a $200,000 research grant to investigate the use of CRISPR-Cas9 gene editing technology as a…
Articles by Patricia Inacio, PhD
Certain genetic defects of maternal origin may be a potential cause of autism spectrum disorder, a neurodevelopmental disorder often found in…
Loss of the maternal copy of the UBE3a gene in a specific set of nerve cells called GABAergic neurons is a…
The seizures of Angelman syndrome patients are dynamic in nature and may change with age. While myoclonic seizures usually happen…
A potential target of the UBE3A enzyme, the protein underlying Angelman syndrome, has been identified in a recent…
The U.S. Food and Drug Administration (FDA) has granted orphan drug designation to GTX-101, GeneTx Biotherapeutics’s investigational compound for the treatment…
Children and young adults with Angelman syndrome rely on a broad set of tools for communication, including speech, facial expressions,…
A mouse model for Angelman and Down syndrome has revealed deficits in touchscreen learning, suggesting that assessing this type of…
Epileptic seizures contribute more than previously thought to autism symptoms in patients with Angelman syndrome, according to researchers. The…
Patients with epilepsy show a pattern of robust brain structural abnormalities, including alterations in the thickness and volume of the…