Neuron activity is impaired in nerve cells located in a specific brain region of genetically engineered mice that lack the UBE3A…
Articles by Joana Carvalho, PhD
Indotecan (LMP400), a compound already in Phase 1 clinical trials, showed promising results as an Angelman syndrome treatment, a mouse study…
Researchers have found a specific type of genetic defect in stem cells derived from a patient with Angelman syndrome…
Humor is essential for the social, developmental and emotional well-being of people affected by different types of intellectual disabilities, including …
Angelman syndrome can occur alongside a condition called dihydropyrimidine dehydrogenase (DPD) deficiency, which has varying degrees of severity and elusive…
Minocycline failed to demonstrate any clinical benefits in the treatment of children and young adults with Angelman syndrome, results…
Deregulation of the brain’s ability to filter real neural signals without becoming overloaded could be the key to understanding the variety…
New instruments for researching Angelman syndrome should be developed to make sure patient outcomes are relevant and properly registered and…