Andrea Lobo, PhD, science writer —

The Foundation for Angelman Syndrome Therapeutics (FAST) has teamed up with the University of Pennsylvania to develop an investigational gene therapy for Angelman syndrome. The nonprofit has sponsored preclinical research at the Gene Therapy Program at the University of Pennsylvania since 2017 to develop a gene therapy…

Changes in the levels of gut bacteria — the gut microbiome — are evident in small and larger animal models of Angelman syndrome, and these alterations may be related to patients’ gastrointestinal symptoms, a study reported. A notable difference between disease models and their healthy counterparts was seen in…