I was disappointed to read the news recently about new data from a Phase 3 clinical trial of an investigational treatment for Angelman syndrome called OV101 (gaboxadol). Developed by Ovid Therapeutics, the experimental treatment did not appear to combat the complexities brought on by Angelman.
Read more
The protein Ube3a, whose defect causes Angelman syndrome, helps regulate connections between brain cells during development. That’s according to the study, “Presynaptic Ube3a E3 ligase promotes synapse elimination through down-regulation of BMP signaling,” which was published in Science. “Our findings reveal the physiological role of Ube3a…
When you’re living with a neurogenetic disorder like Angelman syndrome, you quickly learn that flexibility and change are necessities. I’ve also learned that raising my 13-year-old Angel, Juliana, is a task that requires help and support from others. We lead a fairly simple and average life — or as…
Being overwhelmed is common in life with Angelman syndrome, but columnist Sabrina Johnson has found a new strategy to ease her stress.
Check out Angelman Syndrome News‘ collection of health insights, where you can find a variety of information for patients and caregivers.
Find more answers to your questions about Angelman syndrome in our FAQs section.
Becoming educated and informed about Angelman syndrome is a good first step. Here you’ll find general information about the disease, including diagnosis, symptoms, and causes.
It helps to know others have been where you are now. Here’s a collection of our columnists’ words of wisdom to help you along on your Angelman syndrome journey.
There is no cure for Angelman syndrome yet, but there are treatments that can help manage the disease. Learn more about the approved and experimental therapies here.
Get regular updates to your inbox.